Novel heparin binding peptides

摘要

The present invention provides heparin antagonist peptides. The heparin-binding peptides of the present invention specifically neutralize heparin's conventional anticoagulant properties without causing deleterious hemodynamic side-effects or exacerbation of the proliferative vascular response to injury. More specifically, the heparin-binding compounds of the present invention are short-duration drugs to be used in elective or emergency situations which can safely and specifically neutralize heparin's conventional anticoagulant properties without causing deleterious hemodynamic side-effects or exacerbation of the proliferative vascular response to injury.