MODULATION OF THE BINDING PROPERTIES OF NUCLEIC ACID BINDING PARTNERS

摘要

A method for specifically determining the presence of a target by contacting the target in the presence of other targets with a probe capable of binding to the target to form a complex of the target with the probe, where the contacting is performed in the presence of a compound enhancing the specificity of the binding or the complex formed is contacted with a compound enhancing the specificity of the binding. This method opens the way to a better discrimination between related nucleic acid sequences in diagnostic assays.