发明名称 |
Pharmaceutical compositions containing polyalkylene block copolymers which gel at physiological temperature |
摘要 |
There is disclosed a pharmaceutical composition which gels at physiological temperature. The composition is comprised of a block copolymer containing one or more polyoxyethylene blocks and one or more polyoxy (higher alkylene) blocks wherein at least some of the blocks are linked together by a linking group characterised in that the linking group is an oxymethylene group, and a therapeutic agent. The therapeutic agent is present as (i) nanoparticles of the therapeutic agent having the block copolymer adsorbed on the surface thereof, (ii) a suspension in a solution of the block copolymer, or (iii) as an aqueous solution in a solution of the block copolymer.
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申请公布号 |
US5705194(A) |
申请公布日期 |
1998.01.06 |
申请号 |
US19960727863 |
申请日期 |
1996.10.08 |
申请人 |
NANOSYSTEMS L.L.C. |
发明人 |
WONG, SUI-MING;COOPER, EUGENE R.;XU, SHUQIAN |
分类号 |
A61K9/16;A61K9/14;A61K9/18;A61K31/535;A61K47/34;A61K51/00;(IPC1-7):A61K7/06;A61K7/135 |
主分类号 |
A61K9/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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