| 发明名称 |
Neurotrophic factors having altered receptor binding specificities |
| 摘要 |
A method of altering the receptor binding properties and the stability of neurotrophic factors is set forth. Mutant neurotrophic factors having altered receptor binding specificities are described. Specific embodiments include neurotrophic factors that bind trk receptors but do not bind to the low affinity NGF receptor.
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| 申请公布号 |
US5705617(A) |
申请公布日期 |
1998.01.06 |
| 申请号 |
US19940300044 |
申请日期 |
1994.09.02 |
| 申请人 |
PERSSON, HAKAN BENGT;MOLINER, CARLOS FERNANDO IBANEZ |
发明人 |
PERSSON, HAKAN BENGT;MOLINER, CARLOS FERNANDO IBANEZ |
| 分类号 |
C12N15/09;A61K38/00;C07K14/475;C07K14/48;C12P21/02;C12R1/91;(IPC1-7):C07K14/475 |
主分类号 |
C12N15/09 |
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