HEPARINIZED MEDICAL DEVICES CONTAINING HEPARIN-BINDING GROWTH FACTOR CONJUGATES

摘要

Medical devices are coated with heparin and a heparin-binding growth factor-cytotoxic agent conjugate is bound to the heparin. The devices, including stents, are used to inhibit undesired cell proliferation or kill unwanted cells. A stent coated with heparin and bound with conjugate may be used to inhibit restenosis.