发明名称 |
ACTIVATION OF GROWTH FACTORS BY MATRIX VESICLES. |
摘要 |
<p>Latent growth factors such as TGF'beta' in tissue culture or healing wounds are converted to active form by matrix vesicle extract or through the medium of matrix vesicles stimulated with Regulator of Enhancing Factor (REF). REFs include 1,25-dehydroxy vitamin D and steroid hormones. Matrix vesicles having REF intercalated into the vesicle membrane are provided. Polymeric implant and cell culture scaffolding materials with matrix vesicles, matrix vesicle extract, REF or latent growth factor are also provided.</p> |
申请公布号 |
MX9605459(A) |
申请公布日期 |
1997.12.31 |
申请号 |
MX19960005459 |
申请日期 |
1995.05.19 |
申请人 |
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYS;TEM |
发明人 |
BARBARA D. BOYAN;ZVI SCHWARTZ;LYNDA F. BONEWALD |
分类号 |
A61L27/00;A61F2/28;A61K31/00;A61K31/557;A61K31/565;A61K31/59;A61K35/32;A61K38/18;A61K38/27;A61L27/54;A61L31/16;A61P43/00;C07K14/495;C12N5/077;(IPC1-7):A61K31/00;C12N05/08 |
主分类号 |
A61L27/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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