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发明名称 SPIRO-PIPERIDINE DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS
摘要 Substituted spiro-piperidine derivatives of structural formula (I) are tachykinin receptor antagonists of use, for example, in the treatment or prevention of pain, inflammation, migraine, emesis and postherpetic neuralgia.
申请公布号 WO9749710(A1) 申请公布日期 1997.12.31
申请号 WO1997GB01630 申请日期 1997.06.17
申请人 MERCK SHARP & DOHME LIMITED;BAKER, RAYMOND;CURTIS, NEIL, ROY;ELLIOTT, JASON, MATTHEW;HARRISON, TIMOTHY;HOLLINGWORTH, GREGORY, JOHN;JACKSON, PHILIP, STEPHEN;KULAGOWSKI, JANUSZ, JOZEF;SEWARD, EILEEN, MARY;SWAIN, CHRISTOPHER, JOHN;WILLIAMS, BRIAN, JOHN 发明人 BAKER, RAYMOND;CURTIS, NEIL, ROY;ELLIOTT, JASON, MATTHEW;HARRISON, TIMOTHY;HOLLINGWORTH, GREGORY, JOHN;JACKSON, PHILIP, STEPHEN;KULAGOWSKI, JANUSZ, JOZEF;SEWARD, EILEEN, MARY;SWAIN, CHRISTOPHER, JOHN;WILLIAMS, BRIAN, JOHN
分类号 A61K31/00;A61K31/395;A61K31/435;A61K31/438;A61K31/445;A61K31/451;A61K31/5375;A61K31/5377;A61K31/675;A61P1/00;A61P1/08;A61P25/04;A61P25/06;A61P29/00;A61P43/00;C07D211/56;C07D491/10;C07D491/107;(IPC1-7):C07D491/10 主分类号 A61K31/00
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