SOLID PHASE TYRPHOSTIN LIBRARY LINKED TO MATRICES WITH MEMORIES

摘要

Combinations, called matrices with memories, of matrix materials with memories that are remotely addressable or remotely programmable recording devices or are associated with imprinted symbology are provided. In particular, combinations of matrix materials, memories, and linked molecules that are tyrphostin analogs are provided. The matrix materials are those that are used in as supports in solid phase chemical and biochemical syntheses, immunoassays and hybridization reactions. The matrix materials may additionally include fluophors or other luminescent moieties to produce luminescing matrices with memories. The memories include electronic and optical storage media and also include optical memories, such as bar codes and other machine-readable codes. By virtue of this combination, molecules and biological particles, such as the tyrphostin compounds, that are in proximity or in physical contact with the matrix combination can be labeled by programming the memory with identifying information and can be identified by retrieving the stored information. The tyrphostin compounds, as well as methods of preparing the compounds, are also provided.