发明名称 MONOCLONAL ANTIBODIES TO A NEW ANTIGENIC MARKER IN EPITHELIAL PROSTATIC CELLS AND SERUM OF PROSTATIC CANCER PATIENTS
摘要 Monoclonal antibodies to prostatic cells, are produced by a hybridoma formed by fusing mouse lymphocytes and mouse myeloma cells. The monoclonal antibodies show specificity for a non-soluble, membrane associated, organ specific antigenic determinant limited in its distribution to human prostate epithelial cells and normal prostatic epithelial cells. The monoclonal antibodies, specifically, 7E11 monoclonal antibodies, can be used diagnostically and therapeutically.
申请公布号 CA1339607(C) 申请公布日期 1997.12.30
申请号 CA19890601797 申请日期 1989.06.05
申请人 CYTOGEN CORPORATION 发明人 HOROSZEWICZ, JULIUS S.
分类号 A61K38/00;C07K16/28;C07K16/30;C12N5/20;C12P21/08;(IPC1-7):C12N5/20;A61K39/395;A61K47/48;G01N33/574;G01N33/577 主分类号 A61K38/00
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