| 摘要 |
A peptide of up to about 40 amino acids including the core sequence inclusive of amino acids at positions 92-109 of the p17 gag core protein of HIV-1, such as, Ile-Y1-Y2-Lys-Asp-Thr-Lys-Glu-Ala-Leu-Y3-Lys-Ile-Glu-Glu-Glu-Gln-Asn wherein Y1 is Asp or Glu, Y2 is Val or Ile, and Y3 is Glu or Asp, is effective in inhibiting replication of the HIV virus and provides the basis for a vaccine for treatment or prevention of AIDS.
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