SCREENING METHODS USING MICROBIAL STRAIN POOLS

摘要

Methods of screening for antimicrobial agents or other compounds active on a particular strain are described. These methods use pools of strain of cells or microbes in order to screen for activity on many cellular targets in a single screen. The strain or strains in the pool for which growth is inhibited or stimulated are determined; such identification can also provide a means of identifying the cellular target on which a compound is active.