| 发明名称 |
PROMISCUOUS G-PROTEIN COMPOSITIONS AND THEIR USE |
| 摘要 |
Disclosed are compositions and methods for their use, such as in identifying Gprotein coupled receptors and ligands and compounds that modulate signal transduction. The compositions and methods employ promiscuous G-proteins. Activation of the promiscuous G-protein can be detected in a variety of assays, including assays in which activation is indicated by a change in fluorescence emission of a sample that contains the composition.
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| 申请公布号 |
CA2281898(A1) |
申请公布日期 |
1997.12.24 |
| 申请号 |
CA19972281898 |
申请日期 |
1997.06.20 |
| 申请人 |
AURORA BIOSCIENCES CORPORATION |
发明人 |
ZUKER, CHARLES;SIMON, MELVIN;NEGULESCU, PAUL A.;OFFERMANNS, STEFAN |
| 分类号 |
C07K14/705;C12N15/85;G01N33/50;(IPC1-7):C12Q1/00;C12N15/09;C12N5/10;C12N15/70;C12N15/79;C12N15/81 |
主分类号 |
C07K14/705 |
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