| 发明名称 |
HIV-1 gag cytotoxic T-lymphocyte epitope and method of use |
| 摘要 |
A novel human immunodeficiency virus type 1 (HIV-1) cytotoxic T-lymphocyte (CTL) epitope has been identified in the gag coding region. This epitope corresponds to amino acids 255-269 of Gag and has the following sequence: NH2-asn-pro-pro-ile-pro-val-gly-glu-ile-tyr-lys-arg-trp-ile-ile-COOH. This peptide interacts specifically with human leukocyte antigen-B8 (HLA-B8). This peptide is useful for the identification HIV-1 gag-specific CTL.
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| 申请公布号 |
US5700635(A) |
申请公布日期 |
1997.12.23 |
| 申请号 |
US19940359000 |
申请日期 |
1994.12.19 |
| 申请人 |
UNITED BIOMEDICAL, INC. |
发明人 |
MCMICHAEL, ANDREW JAMES;NIXON, DOUGLAS FRASER;TOWNSEND, ALAIN ROBERT MICHAEL |
| 分类号 |
A61K38/00;A61K39/00;A61K39/21;A61P31/12;A61P31/18;C07K7/08;C07K14/155;C07K14/16;C07K19/00;G01N33/569;(IPC1-7):C12Q1/70;G01N33/53;G01N33/555 |
主分类号 |
A61K38/00 |
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