| 发明名称 |
3'-deoxy or 3'-O-substituted-2',5'-oligoadenylates as antiviral agents |
| 摘要 |
Synthetic analogs of 2',5'-oligoadenylate wherein the aglycon, ribosyl moiety and/or terminal nucleoside have been modified are effective therapeutic agents, particularly against HIV infection. The analogs are utilized in compositions and methods for the treatment of disorders characterized by 2-5A pathway defects.
|
| 申请公布号 |
US5700785(A) |
申请公布日期 |
1997.12.23 |
| 申请号 |
US19940210406 |
申请日期 |
1994.03.14 |
| 申请人 |
TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION |
发明人 |
SUHADOLNIK, ROBERT J.;PFLEIDERER, WOLFGANG |
| 分类号 |
C07H21/00;C07H23/00;(IPC1-7):A61K31/70;C07H21/02 |
主分类号 |
C07H21/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
