发明名称 |
PYRROLIDYLTHIOCARBAPENEM DERIVATIVE |
摘要 |
<p>A pyrrolidylthiocarbapenem derivative represented by Formula I is provided: (I) wherein R1 is hydrogen or lower alkyl; R2, R3 and R4 are hydrogen, lower alkyl which can be substituted or an amino protecting group independently, or R2 and R3 together with a nitrogen atom to which R2 and R3 are bonded form a saturated or unsaturated cyclic group, or R2 and R4, or R3 and R4 together with two nitrogen atoms and one sulfur atom in the sufamide group form a saturated or unsaturated cyclic group; each cyclic group can further include at least one atom selected from the group consisting of oxygen, sulfur and nitrogen, and each cyclic group can be substituted; X1 is hydrogen or a hydroxy protecting group; X2 is hydrogen, a carboxy protecting group, an ammonio group, an alkali metal or an alkaline-earth metal; and Y2 is hydrogen or an amino protecting group.</p> |
申请公布号 |
CA2076430(C) |
申请公布日期 |
1997.12.23 |
申请号 |
CA19922076430 |
申请日期 |
1992.08.19 |
申请人 |
SHIONOGI SEIYAKU KABUSHIKI KAISHA |
发明人 |
IRIE, TADASHI;NISHITANI, YASUHIRO;NISHINO, YUTAKA |
分类号 |
B01J31/02;A61K31/397;A61K31/40;A61K31/41;A61K31/495;A61P31/04;C07B61/00;C07C307/04;C07D207/08;C07D207/12;C07D207/26;C07D207/273;C07D333/20;C07D401/12;C07D403/12;C07D417/06;C07D477/00;C07D477/02;C07D477/14;C07D477/20;C07D501/00;C07D501/04;C07D501/16;C07D501/22;C07D501/46;C07F7/10;C07F9/572;C08L63/00;(IPC1-7):C07D477/00;A61K31/44;A61K31/535 |
主分类号 |
B01J31/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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