Beads having a core coated with an antifungal and a polymer.

摘要

PCT No. PCT/EP93/02327 Sec. 371 Date Mar. 13, 1995 Sec. 102(e) Date Mar. 13, 1995 PCT Filed Aug. 27, 1993 PCT Pub. No. WO94/05263 PCT Pub. Date Mar. 17, 1994The present invention is concerned with beads comprising a 25-30 mesh core, a coating of a hydrophilic polymer and an antifungal agent, and a seal outer coating layer; pharmaceutical dosage forms comprising said beads and a method of preparing said beads. Preferred antifungal agents are lipophilic azole antifungals, such as itraconazole and saperconazole.