HUMAN TYPE II GONADOTROPIN-RELEASING HORMONE RECEPTOR

摘要

A human gonadotropin-releasing hormone receptor, and related compositions and methods are disclosed. The polypeptide has G protein-coupled receptor characteristics and, based on homology to other mammalian gonadotropin-releasing hormone receptors, appears to be the receptor for the conserved GnRH II ligand. The polypeptide may be used within methods to detect the natural human ligand and ligand analogs. The receptor can also be used within methods to influence sexual behavior and reduce proliferation of tumor cells.