| 发明名称 |
Recombinant virus expressing human carcinoembryonic antigen and methods of use thereof |
| 摘要 |
The present invention relates to a recombinant carcinoembryonic antigen (CEA)/vaccinia virus or other viral vector which expresses CEA on the surface of infected cells and which elicits an immune response in vivo directed against CEA or cells expressing CEA and a pharmaceutical composition containing same. The invention also relates to methods of treating patients having tumors in which CEA is expressed and methods of stimulating the immune system against CEA,
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| 申请公布号 |
US5698530(A) |
申请公布日期 |
1997.12.16 |
| 申请号 |
US19940270106 |
申请日期 |
1994.07.01 |
| 申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
SCHLOM, JEFFREY;KANTOR, JUDITH A. |
| 分类号 |
A61K39/00;A61K38/00;A61K38/21;A61K39/12;A61K39/285;A61K45/00;A61P35/00;C07K14/705;C12N5/10;C12N7/00;C12N15/09;(IPC1-7):C12N15/00;C07H21/02;A61K48/00 |
主分类号 |
A61K39/00 |
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