| 发明名称 |
ENHANCED EFFICACY OF LIPOSOMAL ANTISENSE DELIVERY |
| 摘要 |
Pharmaceutical compositions for the treatment of pathologic conditions associated with the overexpression of ICAM-1 in a host. These pharmaceutical compositions comprise an effective amount of an ICAM-1 antisense molecule encapsulated in a lipid mixture which is typically a liposome or lipid particle. The lipid mixture will typically comprise at least two members selected from the group consisting of phospholipids, sterols and cationic lipids.
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| 申请公布号 |
WO9746671(A1) |
申请公布日期 |
1997.12.11 |
| 申请号 |
WO1997CA00347 |
申请日期 |
1997.05.22 |
| 申请人 |
UNIVERSITY OF BRITISH COLUMBIA |
发明人 |
KLIMUK, SANDRA, K.;SEMPLE, SEAN, C.;SCHERRER, PETER;HOPE, MICHAEL, J. |
| 分类号 |
C12N15/09;A61K9/127;A61K31/00;A61K31/70;A61K31/7088;A61K31/711;A61K38/00;A61K47/24;A61K47/28;A61K48/00;A61P1/00;A61P1/16;A61P5/00;A61P9/00;A61P9/10;A61P17/00;A61P19/00;A61P19/02;A61P25/00;A61P25/28;A61P27/00;A61P27/02;A61P31/00;A61P31/12;A61P37/00;A61P37/06;A61P43/00;C12N15/113;(IPC1-7):C12N15/11;C07H21/00 |
主分类号 |
C12N15/09 |
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