发明名称 |
COMPOUNDS ACTIVE AT A NOVEL SITE ON RECEPTOR-OPERATED CALCIUM CHANNELS USEFUL FOR TREATMENT OF NEUROLOGICAL DISORDERS AND DISEASES |
摘要 |
Method and compositions for treating a patient having a neurological disease or disorder, such as stroke, head trauma, spinal cord injury, spinal cord ischemia, ischemia- or hypoxia-induced nerve cell damage, epilepsy, anxiety, neuropsychiatric or cognitive deficits due to ischemia or hypoxia such as those that frequently occur as a consequence of cardiac surgery under cardiopulmonary bypass, or neurodegenerative diseases such as Alzheimer's Disease, Huntington's Disease, Parkinson's Disease, or amyotrophic lateral sclerosis (ALS).
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申请公布号 |
CA2257234(A1) |
申请公布日期 |
1997.12.11 |
申请号 |
CA19962257234 |
申请日期 |
1996.12.11 |
申请人 |
NPS PHARMACEUTICALS, INC. |
发明人 |
SMITH, DARYL L.;BARMORE, ROBERT M.;ARTMAN, LINDA D.;BALANDRIN, MANUEL F.;VANWAGENEN, BRADFORD C.;DELMAR, ERIC G.;MOE, SCOTT T.;MUELLER, ALAN L. |
分类号 |
A61K31/135;A61K31/335;A61K31/44;A61K31/495;A61K31/54;A61K31/55;C07C211/27;C07C211/28;C07C211/29;C07C211/40;C07C215/28;C07C215/54;C07C217/10;C07C217/62;C07C219/22;C07C257/14;C07C323/32;C07D207/08;C07D207/12;C07D211/18;C07D213/38;C07D311/90;C07D313/12;C07D333/20;C07D335/20;C07D337/12;(IPC1-7):C07C211/27 |
主分类号 |
A61K31/135 |
代理机构 |
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代理人 |
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地址 |
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