| 发明名称 |
METHYLATION SPECIFIC DETECTION |
| 摘要 |
The present invention provides a method of PCR, methylation specific PCR (MSP), for rapid identification of DNA methylation patterns in a CpGcontaining nucleic acid. MSP uses the PCR reaction itself to distinguish between methylated and unmethylated DNA, which adds an improved sensitivity of methylation detection.
|
| 申请公布号 |
CA2257104(A1) |
申请公布日期 |
1997.12.11 |
| 申请号 |
CA19972257104 |
申请日期 |
1997.06.03 |
| 申请人 |
THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE |
发明人 |
HERMAN, JAMES G.;BAYLIN, STEPHEN B. |
| 分类号 |
C12N15/09;C12Q1/02;C12Q1/37;C12Q1/44;C12Q1/68;(IPC1-7):C12Q1/68;C07H21/00 |
主分类号 |
C12N15/09 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
