2-BENZYL-4-SULFONYL-4H-ISOQUINOLIN-1,3-DIONES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS

摘要

Anti-inflammatory compounds of formula (I) or (IA) wherein R1 is hydrogen, halogen, C1-4 alkyl, or C1-4 alkoxy; R2 and R3 are the same or different and each is hydrogen, halogen, trifluoromethyl, C1-4 alkyl, or C1-4 alkoxy; and, R4 is C3-4 alkyl, 1,1,1-trifluoroethyl, 2-thienyl, 2-naphthyl, phenyl or phenyl mono- or disubstituted with C1-4 alkyl, C1-4 alkoxy, halogen, trifluoromethyl, or nitro.