NEW AMINO ACID DERIVATIVES AND THEIR USE AS THROMBIN INHIBITORS

摘要

There is provided compounds of formula (I), wherein R<1>, R<2>, R<3>, R<x>, Y, n and B have meanings given in the description which are useful as competitive inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (e.g. thrombosis) or as anticoagulants.