发明名称 |
Compositions and methods for modulating type i interleukin-1 receptor expression |
摘要 |
Compositions and methods are provided for the treatment and diagnosis of diseases amenable to treatment through modulation of type I IL-1 receptor mRNA expression. In accordance with preferred embodiments, oligomers are provided which are specifically hybridizable with DNA or RNA encoding type I interleukin-1 receptor. Methods of modulating type I IL-1 receptor expression and of treating animals suffering from diseases amenable to therapeutic intervention by modulating the expression of type I interleukin-1 receptor with an oligomer specifically hybridizable with DNA or RNA encoding type I interleukin-1 receptor are disclosed. |
申请公布号 |
AU2993397(A) |
申请公布日期 |
1997.12.09 |
申请号 |
AU19970029933 |
申请日期 |
1997.05.12 |
申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
LOREN MIRAGLIA;C. FRANK BENNETT;NICHOLAS DEAN;THOMAS GEIGER |
分类号 |
A61K38/00;C07H21/00;C12N15/113 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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