| 摘要 |
PROBLEM TO BE SOLVED: To obtain a composition for ophthalmology, containing a protein biosynthesis-inhibiting antibacterial antibiotic, and capable of preventing the opacity and refractive defect of an injured tissue due to an ophthalmic operation. SOLUTION: This composition for ophthalmology contains a protein biosynthesis-inhibiting antibacterial antibiotic of amino glycoside, tetracycline, macrolide.lincomycin or chloramphenicol series as an active ingredient. The composition is directly administered to an ocular local site after an ophthalmic operation to suppress the production of metabolites, especially proteins, due to the hyperplasia of inflammatory cells and their ocular tissue cells on the recovery of an ocular tissue wound, to normally maintain the optical transparency and refractivity of the operated ocular tissue, and to prevent a low vision. The composition is prepared into the preparations of eye drops and ointments, and is administered in a concentration of at least 0.5mg/ml. One drop of the eye drop is 40-50μl, and the ointment is coated at a dose of 50mg. The composition is effective for corneal refraction, cataract operation, intraocular lens transplantation, pterygium operation, corneal foreign matter removal, corneal transplantation, keratoplasty, glaucoma operation, etc.
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