发明名称 |
Novel monoclonal antibody and method of immunological analysis of E-D dimer and E-DD/E complex |
摘要 |
A monoclonal antibody which specifically reacts with D-monomer produced by digesting human fibrinogen with granulocyte elastase and D-domain containing digestion products produced by digesting human stabilized fibrin with granulocyte elastase, but does not react with fibrinogen, or fragment X, Y or E produced by digesting fibrinogen with granulocyte elastase is disclosed. The D-dimer or DD/E complex produced by digestion with granulocyte elastase in a sample from a living body can be analyzed without being interferred with fibrinogen, digestion products of fibrinogen with plasmin, or digestion products of stabilized fibrin with plasmin, using the monoclonal antibody. |
申请公布号 |
AU2789297(A) |
申请公布日期 |
1997.12.05 |
申请号 |
AU19970027892 |
申请日期 |
1997.05.15 |
申请人 |
IATRON LABORATORIES, INC. |
发明人 |
ISAO KOHNO;KIMIKO INUZUKA;YUMIKO ITO;KEN FUKUSHI |
分类号 |
C12N15/02;C07K16/00;C07K16/18;C12P21/08;G01N33/573;G01N33/86 |
主分类号 |
C12N15/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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