发明名称 2,4-diaminopyrimidine derivatives
摘要 Compounds of formula I <IMAGE> I wherein R1 is lower-alkoxy, R2 is bromine, lower-alkoxy or hydroxy, R3 is hydrogen, lower-alkyl, cycloalkyl, aryl, heterocyclyl, aralkyl, heterocyclyl-lower-alkyl or cyano, R4 and R5 each independently are hydrogen, lower-alkyl, lower-alkoxy, halogen, hydroxy, amino, di(lower alkyl)amino, cyano or nitro and Q is ethynylene or vinylene, or pharmaceutically usable salts thereof, the use of these compounds and their salts as therapeutically active substances; medicaments based on these substances and their production; the use of these substances as medicaments and for the production of antibacterially-active medicaments; as well as the manufacture of the compounds of formula I and their pharmaceutically acceptable salts and intermediates for their manufacture.
申请公布号 AU2894297(A) 申请公布日期 1997.12.05
申请号 AU19970028942 申请日期 1997.05.07
申请人 F. HOFFMANN-LA ROCHE AG 发明人 PHILIPPE GUERRY;HENRI STALDER;PIERRE-CHARLES WYSS
分类号 A61K31/00;A61K31/505;A61K31/506;A61K31/535;A61K31/5375;A61K31/5377;A61P31/00;A61P31/04;C07D217/06;C07D401/04;C07D401/10;C07D401/14;C07D405/14;C07D409/04;C07D409/14;C07D417/04;C07D417/14 主分类号 A61K31/00
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