发明名称 |
Water soluble high molecular weight polymerized drug preparation |
摘要 |
This invention is a water-soluble high molecular polymerized drug comprising a water-soluble clock copolymer having a hydrophilic segment and a hydrophobic pharmacological-functioning segment to side chain of which a drug is bonded. The hydrophilic first segments of the present invention include polyethylene glycol, polysaccharides, polyacrylamide, and so on. The hydrophobic segments being attached to a drug include polyaspartic acid, polyglutamic acid, polylysine, or derivatives thereof. Drugs to be attached to the hydrophobic segment include anti-cancer drugs, drugs for central nerve, drugs for circulatory organs, and so on.
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申请公布号 |
US5693751(A) |
申请公布日期 |
1997.12.02 |
申请号 |
US19950400905 |
申请日期 |
1995.03.08 |
申请人 |
RESEARCH DEVELOPMENT CORPORATION OF JAPAN |
发明人 |
SAKURAI, YASUHISA;OKANO, TERUO;KATAOKA, KAZUNORI;YAMADA, NORIKO;INOUE, SHOHEI;YOKOYAMA, MASAYUKI |
分类号 |
A61K31/70;A61K9/00;A61K31/785;A61K47/42;A61K47/48;A61P35/00;C08G69/10;C08G69/40;C08G69/48;(IPC1-7):C07K9/00 |
主分类号 |
A61K31/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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