ROTOGRANULATIONS AND TASTE MASKING COATINGS FOR PREPARATION OF CHEWABLE PHARMACEUTICAL TABLETS

摘要

Chewable medicament tablets are made from coated rotogranules of a medicament wherein the rotogranules are formed from a granulation mixture of medicament, e.g. famotidine binder, e.g. polyvinylpyrrolidone, and carrier, e.g. lactose and the rotogranules are coated with cellulose acetate, cellulose acetate butyrate or a combination thereof and polyvinyl pyrrolidone and a process for making such tablets and a method of providing taste masking of medicaments utilizing such coated rotogranules.