摘要 |
The present invention provides a method for producing novel optically active diphosphine compounds [2,2'-bis(di-substituted phosphino)-1,1'-binaphthyl compounds] having a selectivity (chemoselectivity or enantioselectivity) and catalytic activity different from those of conventional BINAP compounds. In a method of the present invention for producing an optically active diphosphine compound (i.e., 2,2-bis(di-substituted phosphino)-1,1'-binaphthyl), 2,2'-bis(trifluoromethanesulfonyloxy)-1,1'-binaphthyl is reacted, in the presence of a transition metal-phosphine complex, with a phosphineoxide compound represented by the following general formula: A2P(O)H wherein A represents a phenyl group; a mono- to tri-substituted phenyl group, wherein each substituent in the substituted phenyl group is individually selected from the group consisting of a halogen atom, a lower alkyl group, a lower alkoxy group or a lower halogenated-alkoxy group such that one or more of the substituents may be the same or different; a naphthyl group; a lower-alkyl naphthyl group; or a lower-alkoxy naphthyl group.
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申请人 |
TAKASAGO INTERNATIONAL CORPORATION |
发明人 |
SAYO, NOBORU;ZHANG, XIAOYONG;OHMOTO, TATSUYA;YOSHIDA, AKIFUMI;YOKOZAWA, TOHRU |