发明名称 |
DNA encoding pasteurella haemolytica PhaI restriction endonuclease and methyltransterase |
摘要 |
Methylation of DNA can be a critical step in the introduction of DNA into P. haemolytica. A methyltransferase has been isolated and molecularly cloned for this purpose. Use of the methyltransferase has allowed construction of defined, attenuated mutants for use as vaccines to protect cattle.
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申请公布号 |
US5693777(A) |
申请公布日期 |
1997.12.02 |
申请号 |
US19960643297 |
申请日期 |
1996.05.08 |
申请人 |
THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE;BIOTECHNOLOGY RESEARCH AND DEVELOPMENT CORPORATION |
发明人 |
BRIGGS, ROBERT E.;TATUM, FRED M. |
分类号 |
A61K39/102;C07K14/285;C12N1/21;C12N9/10;C12N9/22;C12N15/10;C12N15/54;C12N15/55;C12N15/74;(IPC1-7):C07H21/04;C12N9/16 |
主分类号 |
A61K39/102 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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