发明名称 |
Compounds and methods to determine presence of Histoplasma capsulatum |
摘要 |
The present invention combines detection and identification of H. capsulatum in one step, eliminating the need to use DNA probes to react with PCR products in order to distinguish different types of fungi. The purpose of the invention is to provide compounds and methods to directly and specifically identify H. capsulatum in clinical specimens. Specifically, we provide a unique nucleotide sequence from the rRNA gene internal transcribed spacer region I (ITSI) of H. capsulatum and a PCR method which amplifies the unique sequence of H. capsulatum.
|
申请公布号 |
US5693501(A) |
申请公布日期 |
1997.12.02 |
申请号 |
US19950400580 |
申请日期 |
1995.03.08 |
申请人 |
INDIANA UNIVERSITY ADVANCED RESEARCH & TECHNOLOGY INSTITUTE |
发明人 |
LEE, CHAO-HUNG;JIANG, BINGDONG |
分类号 |
C07K14/37;(IPC1-7):C12P19/34;C12Q1/68;C07H21/04;C07H21/02 |
主分类号 |
C07K14/37 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|