发明名称 |
ANTIBODY PURIFICATION BY LOW-PH HYDROPHOBIC INTERACTION CHROMATOGGRAPHY. |
摘要 |
A process for purifying an antibody is provided. In this process, a mixture containing the antibody and a contaminant is subjected to low pH hydrophobic interaction chromatography (LPHIC) at low salt concentration. The antibody is eluted from the column in the fraction which does not bind thereto. This process can be preceded and followed by other purification steps. |
申请公布号 |
MX9707909(A) |
申请公布日期 |
1997.11.29 |
申请号 |
MX19970007909 |
申请日期 |
1996.04.05 |
申请人 |
GENENTECH, INC. |
发明人 |
ERNST H. RINDERKNECHT;GERARDO A. ZAPATA |
分类号 |
C12N15/09;A61K38/00;A61K39/395;A61P37/02;C07K1/20;C07K16/00;C07K16/06;C07K16/28;C07K16/32;C07K16/44;C12N15/13;C12P21/04;C12P21/08 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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