发明名称 PROCESS FOR PREPARING BIOLOGICALLY ACTIVE DERIVATIVES OF 1,2,4-TRIAZOL AND INTERMEDIARIES USEFUL IN THIS PROCESS
摘要 There is disclosed a process for the preparation of fluconazol which is a well-known antifungic agent, as well as pharmaceutically acceptable salts thereof, wherein a new compound having the formula (IV) in which R is H, benzyl, triphenylmethyl and COOR<1>, R<1> being alkyl or aryl, preferably terc-butyl or ethyl and Z is a triazol radical or hydrazine radical, optionally substituted by R, defined as above, optionally in the form of a salt, is reacted with s-triazine. The new compound (IV) is also an object of the invention.
申请公布号 WO9744330(A1) 申请公布日期 1997.11.27
申请号 WO1996ES00245 申请日期 1996.12.20
申请人 KRKA, TOVARNA ZDRAVIL D.D. NOVO MESTO;PALOMO COLL, ALBERTO 发明人 PALOMO COLL, ALBERTO
分类号 C07D403/06;A61K31/4196;C07C241/02;C07C243/18;C07D249/08;C07D521/00;(IPC1-7):C07D249/08 主分类号 C07D403/06
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