CHARACTERIZATION AND USE OF AN ISOLATED URIDINE DIPHOSPHO-GLUCURONOSYLTRANSFERASE
摘要
A uridine diphospho-glucuronosyltransferase (UGTB217) is provided. Methods of producing the enzyme and using the enzyme to identify potential compounds which inhibit or alter the activity of the enzyme are described. In addition, methods of using antibodies to localize the protein, or using the gene sequence or portions thereof for probes or using the gene sequence to produce expression-disrupting sense or antisense DNA fragments thereof, or antisense RNA, are provided.
申请公布号
WO9744466(A1)
申请公布日期
1997.11.27
申请号
WO1997CA00328
申请日期
1997.05.16
申请人
ENDORECHERCHE, INC.;BELANGER, ALAIN;HUM, DEAN, W.;BEAULIEU, MARTIN;LEVESQUE, ERIC
发明人
BELANGER, ALAIN;HUM, DEAN, W.;BEAULIEU, MARTIN;LEVESQUE, ERIC