COMPOSITIONS AND METHODS FOR SCREENING ANTIMICROBIALS

摘要

A method for screening compounds for antimicrobial activity is described tha t utilizes bacterial protein-protein binding in vitro. The method may be performed using immobilized elements and the immobilization may be carried o ut using a variety of immobilization means e.g., columns, beads, adsorbents, nitrocellulose paper, etc.) in order to screen large libraries of compounds.