发明名称 |
HEMATOPOIETIC CYTOKINE RECEPTOR |
摘要 |
Novel receptor polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed. The polypeptides comprise an extracellular ligand-binding domain of a cell-surface receptor that is expressed at high levels in lymphoid tissue, including B-cells and T-cells. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo.
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申请公布号 |
WO9744455(A1) |
申请公布日期 |
1997.11.27 |
申请号 |
WO1997US08502 |
申请日期 |
1997.05.19 |
申请人 |
ZYMOGENETICS, INC. |
发明人 |
BAUMGARTNER, JAMES, W.;FOSTER, DONALD, C.;GRANT, FRANCIS, J.;SPRECHER, CINDY, A. |
分类号 |
C12N15/09;A61K38/00;A61P37/02;C07K14/715;C12N5/10;C12N15/12;(IPC1-7):C12N15/12;C12N15/62;C07K16/28;G01N33/68 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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