| 发明名称 |
Urokinase-type plasminogen activator |
| 摘要 |
<p>The use of substances capable of preventing the binding of a receptor binding form of u-PA to a u-PA receptor (u-PAR) in a mammal and thereby preventing u-PA from converting plasminogen into plasmin thereby preventing cell surface plasminogen activation which is believed to play an important role in tissue remodelling, particularly during cancer invasion for preparing a composition for preventing or counteracting localized proteolytic activity in a mammal, in particular a human.</p> |
| 申请公布号 |
AU683951(B2) |
申请公布日期 |
1997.11.27 |
| 申请号 |
AU19940080463 |
申请日期 |
1994.12.14 |
| 申请人 |
CANCERFORSKNINGSFONDET AF 1989 (FONDEN TIL FREMME AF EKSPERIMEN |
发明人 |
KELD DANO;FRANCESCO BLASI;ANN LOURING ROLDAN;MARIA VITTORIA CUBELLIS;MARIA TERESA MASUCCI;ETTORE APPELLA;W.D. SCHLEUNING;NIELS BEHRENDT;EBBE RONNE;PETER KRISTENSEN;JARI POLLANEN;EEVA-MARJATTA SALONEN;ROSS W. STEPHENS;HANNELE TAPIOVAARA;ANTTI VAHERI;LISBETH BIRK MOLLER;VINCENT ELLIS;LEIF ROGE LUND;MICHAEL PLOUG;CHARLES PYKE;LASZLO PATTHY |
| 分类号 |
A61K38/00;A61K38/18;A61K38/49;A61K38/55;A61K39/395;A61K45/00;A61K49/00;A61K51/00;A61P7/04;A61P35/00;C07K1/22;C07K14/00;C07K14/435;C07K14/705;C07K16/00;C07K16/28;C12N5/10;C12N9/72;C12N15/02;C12N15/09;C12N15/12;C12N15/58;C12P21/02;C12P21/08;C12Q1/68;C12R1/91;G01N33/50;G01N33/53;G01N33/566;G01N33/574;G01N33/577;G01N33/86;(IPC1-7):C12N15/12 |
主分类号 |
A61K38/00 |
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