APPARATUS FOR IMAGING MICROVASCULAR BLOOD FLOW

摘要

An apparatus for measuring and imaging blood perfusion in tissue comprises a monochromatic laser light source (A2); means for shaping the laser light beam; means for irradiating a section of the surface of the tissue (A4) with the laser light beam; means for collecting (A5, A1, A8) light scattered from the irradiated section; an image sensor (A3) comprising a plurality of photodetectors, each photodetector of the sensor being able to receive collected light from a predetermined sub area of the section of the tissue surface and produce a corresponding electrical output signal linearly related to the detected instantaneous laser light intensity; means for processing (4) the electrical output signals from the plurality of photodetectors; means for calculating the average Doppler frequency shift for each sub area from which scattered light is detected; means for producing an image (5) of the blood perfusion in the tissue section irradiated from the processed output signals; and an image display means. The apparatus enables fast tissue blood perfusion imaging to sub second times.