发明名称 |
JET DROPLET DEVICE AND METHOD |
摘要 |
Devices and method are provided for precise reduction of arrays of microspots. A pulse jetting device is employed having a capillary (16) of micron dimensions, with a portion of the capillary proximal to the jetting orifice (60) circumferentially surrounded by a piezoelectric transducer (56). By appropriate design of the capillary (16), orifice (60) and piezoelectric transducer (56), droplets can be formed on a surface, separated by as little as 80 microns center-to-center, and having at least about a 15 micron spacing at the border. The subject subtrate arrays can be used for providing miniaturized arrays of reagents, such as nucleic acids, for detecting the presence of homologous sequences in a sample.
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申请公布号 |
WO9744134(A1) |
申请公布日期 |
1997.11.27 |
申请号 |
WO1997US08135 |
申请日期 |
1997.05.13 |
申请人 |
INCYTE PHARMACEUTICALS, INC.;GAMBLE, RONALD, C.;THERIAULT, THOMAS, P.;BALDESCHWIELER, JOHN |
发明人 |
GAMBLE, RONALD, C.;THERIAULT, THOMAS, P.;BALDESCHWIELER, JOHN |
分类号 |
C12N15/09;B01J19/00;B01L3/02;C40B50/14;C40B60/14;G01N1/28;G01N35/10;(IPC1-7):B01L3/02 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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