| 摘要 |
2-(pyrimidin-4-yloxy)methyl)phenylacetic acid derivatives of formula (I) and their salts and N-oxides are new. R1 = H or 1-4C alkyl; R2 = halo, CH3, CH2CH3, halomethyl or haloethyl; R3 = phenyl, phenoxy, phenoxymethyl, benzyloxy or heteroaryl, (all optionally ring-substituted), H, amino, OH, SH, halo, 1-8C alkyl (optionally substituted by Ar or halo), alkoxy-(1-4C alkyl), alkoxy, mono- or di- alkylamino, alkylthio, alkylsulphoxy, alkylsulphonyl, 3-8C cycloalkyl, trialkylsilyloxy; Ar = phenyl (optionally mono- or di-substituted by halo, CN, NO2, 1-4C alkyl, 1-4C haloalkyl or 1-4C alkoxy); R4 = H, CN, halo, 1-4C alkyl, 1-4C haloalkyl or 1-4C alkoxy; Q = C(=NOCH3)CONHCH3, C(=NOCH3)COOCH3 or N(OCH3)COOCH3; alkyl, alkoxy have 1-8 C unless specified otherwise.
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| 申请人 |
BASF AG, 67063 LUDWIGSHAFEN, DE |
发明人 |
OBERDORF, KLAUS, DR., 69117 HEIDELBERG, DE;GRAMMENOS, WASSILIOS, DR., 67063 LUDWIGSHAFEN, DE;SAUTER, HUBERT, DR., 68167 MANNHEIM, DE;GROTE, THOMAS, DR., 67105 SCHIFFERSTADT, DE;KIRSTGEN, REINHARD, DR., 67434 NEUSTADT, DE;MUELLER, RUTH, DR., 67159 FRIEDELSHEIM, DE;MUELLER, BERND, DR., 67227 FRANKENTAHL, DE;ROEHL, FRANZ, DR., 67105 SCHIFFERSTADT, DE;RACK, MICHAEL, DR., 69123 HEIDELBERG, DE;BAYER, HERBERT, DR., 68159 MANNHEIM, DE;LORENZ, GISELA, DR., 67434 HAMBACH, DE;AMMERMANN, EBERHARD, DR., 64646 HEPPENHEIM, DE;STRATHMANN, SIEGFRIED, DR., 67117 LIMBURGERHOF, DE;HARRIES, VOLKER, DR., 67227 FRANKENTHAL, DE |
