摘要 |
Compounds represented by the formula <IMAGE> wherein A is <IMAGE> R is hydrogen, substituted or unsubstituted lower alkenyl or alkyl of 1 to 8 carbon atoms in the alkyl chain, phenyl or substituted phenyl, R1 is phenyl, substituted phenyl or lower alkyl substituted with phenyl, hydrates thereof, and PHARMACEUTICALLY ACCEPTABLE BASIC SALTS OF SAID COMPOUNDS OR HYDRATES, USEFUL AS ANTIBACTERIAL THERAPEUTIC AGENTS IN THE TREATMENT OF INFECTIOUS DISEASES CAUSED BY Gram-positive and Gram-negative bacteria, particularly Gram-negative bacteria and particularly advantageous because of their stability in aqueous solution are disclosed. |