| 摘要 |
PROBLEM TO BE SOLVED: To obtain a preventive and therapeutic agent for thrombocytopenia by containing parathyroid hormone(PTH) or a PTH derivative. SOLUTION: This preventive and therapeutic agent for thrombocytopenia contains humane PTH (1-84) or its derivative, or PTH or humane PTH (1-34) as an effective ingredient. It is effective for preventing and curing patients suffering from thrombocytopenia, thrombocytopenic peliosis and various diseases expressing bleeding tendency which is seemed to be caused by decrease of platelets. A formulation of the agent can be prepared by a usual formulating method of a peptide in forms of an injection, an encapsulation in microcapsules, an inclusion in a get-like sheet, etc., as the formulation for localization and slow acting. An administration frequency is possible for once a month to an every day administration, preferably once/two weeks to five times/a week, or the everyday administration. The dose is 1-1000μg/kg body weight.
|
