Improved process for preparing polymyxin B/dextran conjugates
摘要
An improved process for producing a water-soluble polymyxin B/dextran conjugate comprises the step of reacting polymyxin B or pharmaceutically acceptable salt thereof with dextran in an aqueous media at a pH of about 9.3 to 10.
申请公布号
US5691304(A)
申请公布日期
1997.11.25
申请号
US19950449436
申请日期
1995.05.25
申请人
NOVARTIS AG
发明人
KAPA, PRASAD;KARDASH, GLEB;KUCEROVY, ANDREW;LAKE, PHILIP;MATTNER, PAUL G.;PETTER, RUSSELL C.;PRASHAD, MAHAVIR;SHARMA, SUSHIL
