发明名称 |
Immunoglobulin superantigen binding to gp 120 from HIV |
摘要 |
VH3 and VH4 type immunoglobulins display superantigen-type binding affinity for the HIV gp120 envelope glycoprotein. VH3 and VH4 type antibody molecules, including IgG and IgM, are shown to suppress HIV infection in vivo and in vitro. Determining the level of such antibody molecules is correlated to the advancement of HIV disease state.
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申请公布号 |
US5691135(A) |
申请公布日期 |
1997.11.25 |
申请号 |
US19940306116 |
申请日期 |
1994.09.14 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
BRAUN, JONATHAN;GOODGLICK, LEE A. |
分类号 |
G01N33/569;(IPC1-7):C12Q1/70 |
主分类号 |
G01N33/569 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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