发明名称 |
Method of administration of IGF-I. |
摘要 |
A method is disclosed that comprises administering insulin-like growth factor-I (IGF-I) to a mammal so as to sustain its biological activity in the mammal comprising administering a therapeutically effective amount of IGF-I to the mammal to provide an exposure to IGF-I for a period of time that stimulates the maximum biological response in the mammal, then discontinuing said administration for a period of time equal to or less than the time period used for administration, and repeating this pattern of administration and discontinuance of administration for a period as long as necessary to achieve or maintain the desired biological response in the mammal. |
申请公布号 |
ZA9603995(B) |
申请公布日期 |
1997.11.20 |
申请号 |
ZA19960003995 |
申请日期 |
1996.05.20 |
申请人 |
GENENTECH, INC. |
发明人 |
WASHINGTON UNIVERSITY;ROSS G. CLARK;NEIL GESUNDHEIT;MARC R. HAMMERMAN;STEVEN B. MILLER |
分类号 |
A61K38/27;A61K38/30;A61K38/55;A61P3/00;A61P3/08;A61P3/10;A61P9/00;A61P13/02;A61P15/00;A61P25/00;A61P37/00 |
主分类号 |
A61K38/27 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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