DP AND E2F PROTEIN NUCLEAR LOCALISATION SIGNALS AND THEIR USE
摘要
The present invention provides nuclear localisation signals derived from the DP-3 and E2F-1 transcription factors and the use of these signals in assays for regulators of cell cycle progression. Such assays involve using the signals to direct a marker gene to the nucleus and determining whether the nuclear localisation of the marker is disrupted by the presence of a putative regulator.
申请公布号
WO9743647(A1)
申请公布日期
1997.11.20
申请号
WO1997GB01324
申请日期
1997.05.15
申请人
MEDICAL RESEARCH COUNCIL;LA THANGUE, NICHOLAS, BARRIE;DE LA LUNA, SUSANA