A drug vessel (1) comprises a vessel body (2) with a narrow neck extending to an open end of a mouth portion (3) thereof, and a stopper (4) fitted in the open end. The stopper (4) comprises a stopper body (5) of an elastomeric material with a through-hole (5a) passing through a central portion thereof along its center axis, and a closing body (6) fitted into the through-hole (5a) of said stopper body (5) to block the through-hole (5a). <IMAGE>