发明名称 |
9-Hydroxy-pyrido[1,2-a]pyrimidin-4-one ether derivatives |
摘要 |
PCT No. PCT/EP94/03804 Sec. 371 Date May 3, 1996 Sec. 102(e) Date May 3, 1996 PCT Filed Nov. 16, 1994 PCT Pub. No. WO95/14691 PCT Pub. Date Jun. 1, 1995The present invention is concerned with novel compounds having the formula <IMAGE> (I) the pharmaceutically acceptable acid addition salts thereof and the stereochemically isomeric forms thereof, wherein Alk represents C1-4alkanediyl; D is a bicyclic heterocycle of formula <IMAGE> (a) orC2-6alkenyl; C2-6alkynyl; C3-6cycloalkyl optionally substituted with C1-4alkyl; C1-19alkyl optionally substituted with C3-6cycloalkyl, halo, C1-6alkyloxy or cyano; and each R2 independently is hydrogen or C1-4alkyl. Novel compounds; compositions; processes for preparing novel compounds and intermediates are described.
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申请公布号 |
US5688799(A) |
申请公布日期 |
1997.11.18 |
申请号 |
US19960637754 |
申请日期 |
1996.03.03 |
申请人 |
JANSSEN PHARMACEUTICA N.V. |
发明人 |
VANDENBERK, JAN;KENNIS, LUDO EDMOND JOSEPHINE |
分类号 |
A61K31/505;A61K31/519;A61P1/00;A61P25/04;A61P25/18;A61P25/20;A61P25/24;A61P25/26;A61P43/00;C07D471/04;(IPC1-7):C07D471/04;C07D239/00;C07D221/00 |
主分类号 |
A61K31/505 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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