发明名称 Spiroazacyclic derivatives as substance P antagonists
摘要 PCT No. PCT/US93/11793 Sec. 371 Date Oct. 12, 1995 Sec. 102(e) Date Oct. 12, 1995 PCT Filed Dec. 10, 1993 PCT Pub. No. WO94/20500 PCT Pub. Date Sep. 15, 1994The present invention relates to novel spirocyclic piperidine derivatives and related compounds and, specifically, to compounds of the formula m are as defined in the specification, and to intermediates used in the synthesis of such compounds. The novel compounds of formula I are useful in the treatment of inflammatory and central nervous system disorders, as well as other disorders.
申请公布号 US5688806(A) 申请公布日期 1997.11.18
申请号 US19950513798 申请日期 1995.10.12
申请人 PFIZER INC. 发明人 DESAI, MANOJ C.;VINCENT, LAWRENCE A.
分类号 A61K31/435;A61P25/00;A61P25/04;A61P25/30;A61P29/00;C07D211/76;C07D471/10;(IPC1-7):A61K31/445 主分类号 A61K31/435
代理机构 代理人
主权项
地址